Cell autonomous requirement of imprinted XCI inextra-embryonic polar trophoblast cells
Feng Wang, Ashmita Chander, Yeonsoo Yoon, Janelle M. Welton, Mary C. Wallingford, Carmen Espejo-Serrano, Francisco Bustos, Greg M. Findlay, Jesse Mager, Ingolf Bach
The paper investigates the role of imprinted XCI in polar trophoblast cells and shows that the Rlim-Rex1 axis is essential for maintaining their fate and preventing early lethality in female mice.
Proceedings of the National Academy of Sciences · Dec 19, 2023Peer-reviewedDevelopmental Biology