Synthetic BiologybioRxivPreprint
Pathway elucidation of pharmaceutical cucurbitacin IIa in Hemsleya chinensis and high-level production of precursor cucurbitadienol in engineered Saccharomyces cerevisiae and Nicotiana benthamiana
Geng Chen, Zhaokuan Guo, Yan Zhao…·Bing Hao
This study elucidates the biosynthetic pathway of cucurbitacin IIa in Hemsleya chinensis and demonstrates high-level production of its precursor in yeast and tobacco.
1 citation