Author
St. Jude Children's Research HospitalORCID 0000-0002-1615-3728Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Leigh E. Fremuth, Diantha van de Vlekkert, Huimin Hu…·Alessandra d’Azzo
This study identifies Neu1 and PPCA as regulators of APP metabolism in Alzheimer's disease, showing their therapeutic potential in reducing amyloid pathology.
Leigh E. Fremuth, Huimin Hu, Diantha van de Vlekkert…·Alessandra d’Azzo
This study shows that Neu1 regulates microglial function by modulating Trem2 sialylation, affecting phagocytosis and cytokine production.
Jason A. Weesner, Ida Annunziata, Diantha van de Vlekkert…·Alessandra d’Azzo
This study shows that altered GM1 catabolism disrupts ER-PM junctions, increases Ca2+ signaling, and promotes synaptic spine formation in a neurodegenerative disease model.