Author

Mitch A. Phelps

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research InstituteORCID 0000-0002-1615-5280Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

David Paul CarboneiD· 1 shared Deepti MathuriD· 1 shared Dwight Hall OweniD· 1 shared Elaine R. MardisiD· 1 shared Katarina Benejova· 1 shared Kristina Travis· 1 shared Liza MakowskiiD· 1 shared Martin BenejiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

David Paul CarboneORCID

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1 paper

Recent·Most cited

Targeting alpha-ketoglutarate starvation within the tumor-immune microenvironment rescues T cell effector function in cancer immunotherapy

Katarina Benejova, Kristina Travis, Deepti Mathur, No‐Joon Song, Zihai Li, Mitch A. Phelps, Elaine R. Mardis, Liza Makowski, David Paul Carbone, Dwight Hall Owen, Martin Benej

This study shows that supplementing alpha-ketoglutarate (aKG) improves T cell function and immunotherapy effectiveness in NSCLC by reversing epigenetic changes associated with T cell exhaustion.

bioRxiv · Oct 27, 2026 · PreprintCancer Biology