Author

Caroline M. Weisman

Princeton UniversityORCID 0000-0002-1648-6776Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:chromatin & epigenetic regulation· 2 Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1

Frequent Co-Authors

Amy Karol WalkeriD· 1 shared Andrew W. MurrayiD· 1 shared Daniel P HigginsiD· 1 shared Dominique S. LuiiD· 1 shared Frank D’AgostinoiD· 1 shared Sean R. EddyiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 7 mutual co-author links

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1 shared paperGenomics

Amy Karol WalkerORCID

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4 papers

Recent·Most cited

Tinkering loci: hubs of gene birth in an animal genome

Caroline M. Weisman

The paper identifies 'tinkering loci' in Drosophila genomes that accelerate gene birth by concentrating duplicated gene fragments and facilitating composite gene creation.

bioRxiv · Sep 8, 2026 · PreprintEvolutionary Biology

Exon shuffling hotspots in an animal genome

Caroline M. Weisman

The paper identifies exon shuffling hotspots in Drosophila affinis genomes, showing they facilitate rapid gene creation and family formation through genomic sequence rearrangement.

bioRxiv · Oct 28, 2025 · PreprintEvolutionary Biology

WormCat 2.0 defines characteristics and conservation of poorly annotated genes in Caenorhabditis elegans

Daniel P Higgins, Caroline M. Weisman, Dominique S. Lui, Frank D’Agostino, Amy Karol Walker

WormCat 2.0 identifies poorly annotated genes in C. elegans and shows they have human orthologs with limited annotation.

Genetics · May 19, 2022Peer-reviewedGenomics

Mixing genome annotation methods in a comparative analysis inflates the apparent number of lineage-specific genes

Caroline M. Weisman, Andrew W. Murray, Sean R. Eddy

The paper shows that using different gene annotation methods in comparative genomics can falsely increase the number of lineage-specific genes by up to 15-fold.

Current Biology · May 18, 2022Peer-reviewedGenomics