Author

Dominique S. Lui

University of Massachusetts Chan Medical SchoolORCID 0000-0003-4815-6242Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Amy Karol WalkeriD· 2 shared Daniel P HigginsiD· 2 shared Adwait Anand GodboleiD· 1 shared Athena L. Munden· 1 shared Benjamin R. HarrisoniD· 1 shared Caroline A. LewisiD· 1 shared Caroline M. WeismaniD· 1 shared Dana L. MilleriD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCell Biology

Amy Karol WalkerORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintFeb 20, 2025

Functional Specialization of S-Adenosylmethionine Synthases Links Phosphatidylcholine to Mitochondrial Function and Stress Survival

Athena L. Munden, Dominique S. Lui, Daniel P Higgins…·Amy Karol Walker

The paper investigates the functional specialization of SAM synthases in C. elegans, showing that SAMS-1 affects mitochondrial function and stress survival through phosphatidylcholine, while SAMS-4 is critical for methylation reactions.

DOI 10.1101/2025.02.20.639242

C. elegansexperimental assay

𝕏 PostBluesky

GenomicsGeneticsPeer-reviewedMay 19, 2022

WormCat 2.0 defines characteristics and conservation of poorly annotated genes in Caenorhabditis elegans

Daniel P Higgins, Caroline M. Weisman, Dominique S. Lui…·Amy Karol Walker

WormCat 2.0 identifies poorly annotated genes in C. elegans and shows they have human orthologs with limited annotation.

50 citations

C. eleganswhole-genome sequencing

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