Author

Debomoy K. Lahiri

Indiana University IndianapolisORCID 0000-0002-1664-5933Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Research Focus:GWAS / association mapping· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Bryan MaloneyiD· 3 shared John S. BeckiD· 2 shared Kwangsik T. NhoiD· 2 shared Ruizhi WangiD· 2 shared Scott CountsiD· 2 shared Calvert Schmued· 1 shared Chhanda BoseiD· 1 shared Erika Orlov· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersNeuroscience

Bryan MaloneyORCID

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4 papers

Recent·Most cited

Oral administration of 1,10-phenanthroline-5-amine (PAA) significantly reduced amyloid plaque burden compared with untreated APP/PS1 mice.

Larry C. Schmued, Bryan Maloney, Calvert Schmued, Kaitlyn Gregerson, Debomoy K. Lahiri

This study validates that oral PAA reduces amyloid plaque burden in APP/PS1 mice and shows PAA directly binds to amyloid plaques in vitro.

bioRxiv · Jul 30, 2026 · PreprintNeuroscience

MicroRNA-181 influences Alzheimer's risk by regulating neprilysin and microtubule-associated tau pathways, offering a novel target

Ruizhi Wang, Bryan Maloney, Kwangsik T. Nho, John S. Beck, Scott Counts, Debomoy K. Lahiri

The paper identifies miR-181's role in regulating neprilysin and tau pathways linked to Alzheimer's risk, suggesting it as a novel therapeutic target.

bioRxiv · Jun 16, 2026 · PreprintNeuroscience

Human microRNA-153-3p targets specific neuronal genes and is associated with the risk of Alzheimer's disease.

Ruizhi Wang, Bryan Maloney, Kwangsik T. Nho, John S. Beck, Scott Counts, Debomoy K. Lahiri

This study identifies miR-153-3p as a regulator of neuronal genes and shows its association with Alzheimer's disease risk and pathogenesis.

bioRxiv · Sep 7, 2024 · PreprintNeuroscience

Synaptosome microRNAs regulate synapse functions in Alzheimer's disease

Subodh Kumar, Erika Orlov, Prashanth Gowda, Chhanda Bose, Russell Howard Swerdlow, Debomoy K. Lahiri, P. Hemachandra Reddy

The paper compares miRNA expression in synaptosomes and cytosol from AD and control brains, identifying differentially expressed miRNAs and their potential roles in synapse function.

npj Genomic Medicine · Aug 8, 2022Peer-reviewedNeuroscience