Sreemol Gokuladhas

Establishing gene regulatory networks from Parkinson's disease risk loci

This study identifies gene regulatory networks influenced by Parkinson's disease risk SNPs using eQTL and chromosomal conformation data across multiple tissues.

Deciphering the genetic links between NAFLD and co-occurring conditions using a liver gene regulatory network

The paper constructs a liver-specific gene regulatory network to identify genetic links between NAFLD and co-occurring conditions, revealing shared regulatory mechanisms.

Unravelling the shared genetic mechanisms underlying 18 autoimmune diseases using a systems approach

This study identifies shared genetic mechanisms across 18 autoimmune diseases by integrating chromatin contact, expression quantitative trait loci, and protein-protein interaction data.

Shared regulatory pathways reveal novel genetic correlations between grip strength and neuromuscular disorders

The paper identifies shared regulatory pathways between grip strength and neuromuscular disorders using eQTL and Hi-C data, revealing common drug targets and biological mechanisms.

A transcription regulatory network within the ACE2 locus may promote a pro-viral environment for SARS-CoV-2 by modulating expression of host factors.

The paper identifies regulatory elements within the ACE2 locus that control host gene expression, suggesting they may contribute to a pro-viral environment for SARS-CoV-2.