Denis M. Nyaga

This paper benchmarks 7 TR genotyping tools using Nanopore long-read data, finding that no single tool is best across all metrics, and that sequence-level accuracy is crucial for clinical and population studies.

This study evaluates genome-wide DNA methylation analysis in genetically unsolved DEEs, identifying 10 causative or candidate genetic causes and refining a CHD2 episignature.

The paper benchmarks nanopore sequencing performance and validates a rapid genomics pipeline for clinical use in New Zealand.

The paper identifies regulatory elements within the ACE2 locus that control host gene expression, suggesting they may contribute to a pro-viral environment for SARS-CoV-2.

This study identifies immune regulatory networks influenced by T1D-associated genetic variants using 3D genome organization and gene expression data.