Tayaza Fadason

This study identifies genetic variants and genes associated with COPD and co-occurring traits by integrating multi-omics data and gene regulatory networks.

This paper uses local Bayesian regressions to identify genomic regions with significant genetic covariance between chronic kidney disease and hyperuricemia, finding both novel and previously reported shared loci.

This study identifies gene regulatory networks influenced by Parkinson's disease risk SNPs using eQTL and chromosomal conformation data across multiple tissues.

The paper constructs a liver-specific gene regulatory network to identify genetic links between NAFLD and co-occurring conditions, revealing shared regulatory mechanisms.

This study identifies shared genetic mechanisms across 18 autoimmune diseases by integrating chromatin contact, expression quantitative trait loci, and protein-protein interaction data.

The paper identifies ASD-associated SNPs in fetal and adult cortex tissues and links them to regulatory processes and pathways, highlighting differences in their impact across developmental stages.

The paper identifies regulatory elements within the ACE2 locus that control host gene expression, suggesting they may contribute to a pro-viral environment for SARS-CoV-2.

This study integrates chromatin interactions and genetic data to identify SNP-gene-metabolite associations across multiple tissues.

This paper identifies 15 novel serum urate loci and links them to 44 genes, revealing new molecular mechanisms of urate control through genomic and eQTL analysis.

The paper identifies genetic drivers of multimorbidities by analyzing chromatin interactions and eQTL data to uncover regulatory interactions across multiple phenotypes.