Author

David R. Mark

University of GlasgowORCID 0000-0002-1688-5224Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Andrew J. RoeiD· 2 shared Rebecca E. McHughiD· 2 shared Gill R. DouceiD· 1 shared Kabo R. WaleiD· 1 shared Mia Y Trolan· 1 shared Nicky O’BoyleiD· 1 shared Samantha K. TuckeriD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 15 mutual co-author links

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2 shared papersMicrobiology

Andrew J. RoeORCID

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2 papers

Recent·Most cited

MicrobiologyOpen BiologyPeer-reviewedNov 1, 2024

Aurodox, a polyketide from Streptomyces goldiniensis, inhibits transcription of the type III secretion system of multiple Gram-negative pathogens

David R. Mark, Nicky O’Boyle, Kabo R. Wale…·Andrew J. Roe

This study investigates aurodox's effect on T3SS in multiple Gram-negative pathogens, showing it inhibits some but not all T3SS systems, with selectivity observed across different strains.

3 citations

E. colimouse

𝕏 PostBluesky

MicrobiologybioRxivPreprintJul 5, 2024

The Enemy Within: how pathogen-free are your commercial specific pathogen-free mice?

David R. Mark, Mia Y Trolan, Gill R. Douce…·Rebecca E. McHugh

The paper isolates and characterizes an E. coli O157:H7 strain from commercial specific-pathogen-free mice, revealing limitations in current screening systems.

DOI 10.1101/2024.07.05.602177

mouseDNA methylation

𝕏 PostBluesky