Author

Zehra Visram

ORCID 0000-0002-1691-7396Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Adriana BadarauiD· 2 shared Andrea Majoros-Hashempour· 2 shared Benedikt Bauer· 2 shared Donaat KestemontiD· 2 shared Julia Schmidt· 2 shared Lorenzo CorsiniiD· 2 shared Manuel Zerbs· 2 shared Marina von Freyberg· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioengineering

Adriana BadarauORCID

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2 papers

Recent·Most cited

A chimeric, half-life extended lysin with a unique mode of action

Zehra Visram, Donaat Kestemont, Benedikt Bauer, Renping Qiao, Svetlana Ðurica-Mitić, Andrea Majoros-Hashempour, Julia Schmidt, Rocío Berdaguer, Karsten Krey, Michele Mutti, Manuel Zerbs, Marina von Freyberg, Lorenzo Corsini, Adriana Badarau

This paper develops a half-life extended lysin by fusing it to an Fc fragment, showing improved efficacy against staphylococcal infections through targeted release.

Frontiers in Microbiology · Aug 21, 2026Peer-reviewedBioengineering

Multi-dimensional optimization of a lysin towards a ribolysin against life-threatening S. aureus infections: Fc-LysM-CHAP and its strong synergy with standard of care antibiotics

Adriana Badarau, Benedikt Bauer, Zehra Visram, Renping Qiao, Andrea Majoros-Hashempour, Johannes Söllner, Svetlana Ðurica-Mitić, Orla M. Dunne, Robert Kluj, Donaat Kestemont, Ann-Katrin Kieninger, Monika Kulig, Rocío Berdaguer, Timo Schwebs, Manuel Zerbs, , Lorenzo Corsini

This paper develops an Fc-fused lysin, Fc-LysM-CHAP, optimized for improved pharmacokinetics and synergy with antibiotics against S. aureus infections.

bioRxiv · May 8, 2026 · PreprintMicrobiology