Svetlana Ðurica-Mitić

This paper develops a half-life extended lysin by fusing it to an Fc fragment, showing improved efficacy against staphylococcal infections through targeted release.

This study identifies resistance determinants to antisense antibiotics by analyzing mutations in gram-negative pathogens exposed to CPP-PNA conjugates, revealing adaptation strategies and resistance mechanisms.

This paper develops an Fc-fused lysin, Fc-LysM-CHAP, optimized for improved pharmacokinetics and synergy with antibiotics against S. aureus infections.

This study uses non-genetic mRNA silencing to identify essential genes in phage-host interactions, revealing new proteins critical for phage replication and host response.

The paper reports the cryoEM structures of the RapZ:GlmZ complex and its interaction with RNase E, revealing mechanisms of RNA regulation in bacterial cell envelope biogenesis.