Mechanical Cues Regulate Cargo Sorting and Export at the Golgi
Greta Serafino, Stefania Forciniti, Edoardo Scarpa, Antonio Ranieri, Lucia Santorelli, Gabriella De Blasi, Sara Costantini, Eunjoo Hwang Lee, Antonio Galeone, Alessia Calcagnì, Marinella Pirozzi, Loretta L. del Mercato, Rossella Venditti, Giovanni D’Angelo, Seetharaman Parashuraman, , Riccardo Rizzo
This study identifies a mechanical regulation pathway involving Src-FAK-AMPK-GBF1 that controls cargo sorting and secretion from the Golgi in response to substrate stiffness.
Advanced Science · Oct 14, 2025Peer-reviewedCell Biology