Antonio Galeone

The paper identifies TUSC3 as a gatekeeper regulating glycan trimming of BMP4/Dpp to control ERQC entry and BMP signaling.

This study develops a dual CAR-T therapy targeting CD33 and TIM-3 in AML, showing improved specificity and efficacy through glycosylation-modulated TIM-3 recognition.

This study shows that mesodermal-specific MECP2 overexpression in Drosophila causes muscle and gut defects, which are rescued by butyrate and valproate.

This study identifies a mechanical regulation pathway involving Src-FAK-AMPK-GBF1 that controls cargo sorting and secretion from the Golgi in response to substrate stiffness.

This study shows that loss of Drosophila N-glycanase 1 causes gut barrier defects, leading to immune activation and lipid catabolism, which contribute to lethality through non-infectious mechanisms.