Molecular BiologyRetrovirologyPeer-reviewed
HIV-2/SIV Vpx antagonises NF-B activation by targeting p65
Douglas Fink, James Cai, Matthew V. X. Whelan…·Rebecca P. Sumner
This paper demonstrates that HIV-2/SIV Vpx antagonizes NF-κB activation by inhibiting p65 nuclear translocation, independent of known cofactors, and shows this mechanism is conserved across lentiviruses.
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