Developmental BiologyFrontiers in Cellular NeurosciencePeer-reviewed
Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse
Katrina S. Hofstetter, Paula M. Haas, Jonathon P. Kuntz…·Sabine Fuhrmann
This study shows that loss of Cdc42 in mice causes defects in optic cup morphogenesis, leading to microphthalmia and coloboma due to impaired cell polarity, junctions, and proliferation.
2 citations