Developmental BiologyGeneticsPeer-reviewed
High levels of Dorsal transcription factor downregulate, not promote, snail expression by regulating enhancer action
Leslie Dunipace, James M. McGehee, Jihyun Irizarry, Angelike Stathopoulos
The paper shows that high Dorsal levels suppress snail expression by limiting enhancer activity, while low levels promote it, through dynamic regulation of enhancer interactions.
5 citations