Chunhui Cai

The paper identifies pervasive somatic NF1 mutations in oligodendrocyte precursors in NF-1 patients, showing clonal selection and spatial bias, and links CDKN2A loss to tumor progression.

This study shows that Trr1 depletion in C. albicans increases sensitivity to antifungals and cell wall stress by disrupting metabolic pathways and cell wall synthesis.

This study examines how dup15q affects gene expression and chromatin accessibility in specific brain cell types, finding cell-type-specific effects and distinct regulatory mechanisms in ASD and dup15q.

This paper introduces a Bayesian method to identify causative genome alterations in individual tumors by inferring their impact on transcriptomic changes.