Molecular BiologybioRxivPreprint
Cryo-EM reveals the central steps of mitochondrial complex III assembly and the cooperative assembly of supercomplex CIII2CIV
Ahad Ali Kazmi, Andrea Gottinger, Marine S. Huhardeaux…·Irene Vercellino
This paper uses cryo-EM to reveal the assembly mechanism of mitochondrial complex III and supercomplex CIII2CIV, showing that subunit incorporation and folding are uncoupled and assembly proceeds non-parallel after dimerization.
DOI 10.64898/2026.09.07.749710