Harshil Patel

This study identifies distinct roles of ATRX in safeguarding genome and telomere integrity through interactions with CST and 9-1-1 complexes, revealing context-dependent mechanisms.

This study benchmarks Nanopore long read RNA sequencing in human cell lines, showing improved isoform resolution compared to short reads.

The paper identifies three novel components of the yeast m6A methyltransferase complex and reveals their distinct m6A-dependent and independent roles in meiosis and mating.

This study shows ASCL1 interacts with mSWI/SNF complexes to regulate chromatin structure and gene expression during human neurogenesis.

This study shows that RSC and GRFs control promoter directionality by reducing divergent noncoding transcription.

The paper shows that Sox2 levels determine how WNT signaling affects epiblast progenitors, influencing pluripotency and mesodermal differentiation through changes in chromatin occupancy and regulatory element selection.

A peer-reviewed, community-run framework for Nextflow analysis pipelines, plus helper tooling, meant to make workflows portable and reproducible across institutions rather than tied to one cluster.

The paper shows that ERK1/2 signaling decline promotes neural differentiation by reducing polycomb repressive complex occupancy at neural genes, increasing chromatin accessibility, and enabling transcription.

This study shows how the transcription factor Rap1 represses divergent noncoding transcription in yeast by preventing transcription initiation at cryptic promoters.