Sung‐Joon Park

This paper identifies six PD subgroups based on cell-type-specific genetic networks and links NRG6 to reduced myelin integrity in oligodendrocytes.

STAIG integrates spatial transcriptomics data with histological images using graph-contrastive learning to analyze spatial domains without prealignment.

The paper develops a computational method to model interactions between proximal and distal regulators in B cell differentiation, finding that distal regulators fine-tune transcription and modular regulators are involved in chromatin reorganization.

HyGAnno transfers cell type labels from scRNA-seq to scATAC-seq using a graph neural network, improving annotation accuracy and robustness.

This study identifies hysteresis genes in macrophage polarization and shows that AP-1 and CTCF regulate chromatin state changes during de/repolarization.

The paper develops a computational method to detect microbial contaminants in NGS data and assesses their functional impact on host molecular pathways.