Author

Hugo Siegfried

Centre National de la Recherche ScientifiqueORCID 0000-0002-1785-9589Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:development & morphogenesis· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Sandrine Etienne‐MannevilleiD· 2 shared Agathe VerraesiD· 1 shared Anaïs VertueuxiD· 1 shared Anne‐Marie TassiniD· 1 shared Atef AsnaciosiD· 1 shared Cathy L. JacksoniD· 1 shared Christie OuaddiiD· 1 shared David PereiraiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

Sandrine Etienne‐MannevilleORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 30, 2025

KIAA1217/SKT and its paralog p140Cap are centrosomal proteins that regulate ciliogenesis through Src family signaling pathway.

Logan Greibill, Lucie Raimbourg, Hugo Siegfried…·Anne‐Marie Tassin

DOI 10.1101/2025.10.30.685566

humanexperimental assay

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Cell BiologybioRxivPreprintOct 22, 2025

Lipid transfer by ORP3 is required for the regulation of PI4P and PI(4,5)P2 at the plasma membrane in mitosis

Anaïs Vertueux, Agathe Verraes, Christie Ouaddi…·Jean‐Marc Verbavatz

This study shows that ORP3 lipid transfer is essential for regulating PI4P and PI(4,5)P2 levels at the plasma membrane during mitosis, affecting cell division and preventing genetic instability.

DOI 10.1101/2025.10.22.684039

humanproteomics

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Cancer BiologybioRxivPreprintJun 27, 2025

Intratumoral Heterogeneity of Vimentin Modulates Nuclear Mechanotransduction, DNA Damage Response and Cancer Cell Survival

Elvira Infante, Emmanuel Terriac, Matthieu Gélin…·Sandrine Etienne‐Manneville

The paper shows that vimentin absence in glioblastoma cells affects nuclear mechanotransduction, DNA damage response, and cell survival under stress.

2 citations

humanbulk RNA-seq

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