Enrique Amaya

The roles of NADPH oxidases during adult zebrafish fin regeneration

This study identifies Duox as a key NADPH oxidase for ROS production and fin regeneration in adult zebrafish, with secondary roles for Nox1-4 and a circadian rhythm in ROS levels.

Aerobic glycolysis is important for zebrafish larval wound closure and tail regeneration

This study shows aerobic glycolysis is essential for zebrafish larval wound closure and tail regeneration, with lactate levels increasing rapidly after injury and being inhibited by glycolysis blockers.

Zebrafish duox mutations provide a model for human congenital hypothyroidism

This study shows that zebrafish duox mutants exhibit congenital hypothyroidism-like phenotypes, which can be rescued by T4 treatment, suggesting their utility as a model for human hypothyroidism.

Ca2+-induced mitochondrial ROS regulate the early embryonic cell cycle

This study shows that Ca2+-induced mitochondrial ROS regulate the early cell cycle in Xenopus embryos by controlling Cdc25C activity.

Elevated and sustained reactive oxygen species levels facilitate mesoderm formation during early Xenopus development

The paper shows that sustained elevated reactive oxygen species (ROS) levels during early Xenopus development are essential for mesoderm formation by promoting growth factor signaling.