Jorge Amich

M-CSF stimulated alveolar macrophages safeguard from invasive aspergillosis

This study shows that M-CSF enhances alveolar macrophage function to protect against invasive aspergillosis in immunocompromised mice.

Establishing thresholds for azole tolerance and persistence in Aspergillus fumigatus to study their impact on voriconazole treatment in vivo

This study establishes thresholds for azole tolerance and persistence in Aspergillus fumigatus and shows tolerance negatively affects voriconazole treatment efficacy in a Galleria mellonella model.

The sulfur-related metabolic status of Aspergillus fumigatus during infection reveals cytosolic serine hydroxymethyltransferase as a promising antifungal target.

The paper identifies genes involved in sulfur metabolism in Aspergillus fumigatus during infection, highlighting ShmB as a promising antifungal target due to its essential role in virulence and structural differences from the human enzyme.

The roles of NADPH oxidases during adult zebrafish fin regeneration

This study identifies Duox as a key NADPH oxidase for ROS production and fin regeneration in adult zebrafish, with secondary roles for Nox1-4 and a circadian rhythm in ROS levels.