Shoko Ishibashi

This study identifies Duox as a key NADPH oxidase for ROS production and fin regeneration in adult zebrafish, with secondary roles for Nox1-4 and a circadian rhythm in ROS levels.

This study shows that zebrafish duox mutants exhibit congenital hypothyroidism-like phenotypes, which can be rescued by T4 treatment, suggesting their utility as a model for human hypothyroidism.

This study shows that Ca2+-induced mitochondrial ROS regulate the early cell cycle in Xenopus embryos by controlling Cdc25C activity.

The paper shows that sustained elevated reactive oxygen species (ROS) levels during early Xenopus development are essential for mesoderm formation by promoting growth factor signaling.