Kunal Chopra

This study shows that HES1 protein oscillations are necessary for ER+ breast cancer cells to re-enter the cell cycle, and disrupting these oscillations prevents reactivation of dormant cells.

The paper shows that cell coupling compensates for altered Her6 dynamics in zebrafish neural progenitors, maintaining phenotypic robustness despite single-cell expression changes.

This study identifies Duox as a key NADPH oxidase for ROS production and fin regeneration in adult zebrafish, with secondary roles for Nox1-4 and a circadian rhythm in ROS levels.

This study shows that zebrafish duox mutants exhibit congenital hypothyroidism-like phenotypes, which can be rescued by T4 treatment, suggesting their utility as a model for human hypothyroidism.