NeuroscienceNature CommunicationsPeer-reviewed
Deep transcriptome profiling of human hypothalamic agouti-related protein and proopiomelanocortin neurons regulating energy homeostasis
Szabolcs Takács, Katalin Skrapits, Balázs Göcz…·Erik Hrabovszky
The paper develops and validates an IHC/LCM-Seq method to profile transcriptomes of AgRP and POMC neurons in human hypothalamus, revealing distinct gene expression patterns and potential pharmacological targets for weight management.
DOI 10.1038/s41467-026-76688-w