Author
University of Wisconsin–MadisonORCID 0000-0002-1816-1721Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Matthew J. Freeman, Noah J. Eral, Abigail M. Debrine…·John‐Demian Sauer
This study identifies PDH complex defects in L. monocytogenes as critical for intracellular survival, showing that PDH mutants fail to utilize PTS-dependent carbon sources, leading to reduced virulence.
Matthew J. Freeman, Noah J. Eral, John‐Demian Sauer
This study shows that Listeria monocytogenes uses phosphotransferase systems (PTS) for intracellular growth and virulence, contradicting previous models that excluded PTS in cytosolic metabolism.
Cheta Siletti, Matthew J. Freeman, Hung H. Dang…·TuAnh Ngoc Huynh
This study shows that c-di-AMP accumulation in Listeria monocytogenes disrupts glutathione metabolism, leading to reduced virulence gene expression and attenuated pathogenesis.