Author

Ben S. Duggan

Indiana University BloomingtonORCID 0000-0002-1819-2130Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Research Focus:dimensionality reduction· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:software / tool· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Brandon Fischer· 1 shared Jie ZhangiD· 1 shared John MetzcariD· 1 shared Kun HuangiD· 1 shared Matthew Murphy· 1 shared Michael F. Sharpnack· 1 shared Paul MackliniD· 1 shared Randy W. HeilandiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperSystems Biology

Brandon Fischer

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2 papers

Recent·Most cited

Systems BiologyBulletin of Mathematical BiologyPeer-reviewedFeb 12, 2025

A simple framework for agent-based modeling with extracellular matrix

John Metzcar, Ben S. Duggan, Brandon Fischer…·Paul Macklin

The paper introduces a simplified agent-based framework for modeling cell-ECM interactions using PhysiCell, demonstrating its utility in various biological processes.

14 citationstop 3%

experimental assaybenchmarking

𝕏 PostBluesky

BioinformaticsBriefings in BioinformaticsPeer-reviewedMar 10, 2022

SPCS: A Spatial and Pattern Combined Smoothing Method of Spatial Transcriptomic Expression

Yusong Liu, Tongxin Wang, Ben S. Duggan…·Travis S. Johnson

This paper introduces SPCS, a two-factor smoothing method for spatial transcriptomics data that improves separability and biological interpretability compared to one-factor methods.

24 citations

humanspatial transcriptomics

𝕏 PostBluesky