Author

Thomas Knösel

Pathologisches InstitutORCID 0000-0002-1822-0197Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:spatial transcriptomics· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Andreas MöckiD· 2 shared Frederick KlauscheniD· 2 shared Lars Hartwin LindneriD· 2 shared Linda BergmayriD· 2 shared Luc M. BerclaziD· 2 shared Anna KübleriD· 1 shared Anton Burkhard‐MeieriD· 1 shared C Wang· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Andreas MöckORCID

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2 papers

Recent·Most cited

Matched primary-metastasis single-nucleus and spatial profiling of leiomyosarcoma identifies antigen-presenting fibroblasts at the tumor-organ interface

Anna Kübler, Linda Bergmayr, Thomas Knösel, Philipp Sebastian Jurmeister, Yauheniya Zhdanovich, Luc M. Berclaz, Josephine Deleuran Hendriksen, Dilara Karaoğlu, Romy L. Zuber, Michael Hoberger, Dorit Di Gioia, Markus Albertsmeier, Matthias Grube, Martin Trepel, Carolin Mogler, , Andreas Möck

This study uses single-nucleus RNA sequencing and spatial transcriptomics to compare primary and metastatic leiomyosarcoma, identifying antigen-presenting fibroblasts associated with metastasis.

bioRxiv · Oct 5, 2026 · PreprintCancer Biology

Pan-cancer virtual spatial transcriptomics from routine histology with Phoenix

Manuel Tran, Rushin H. Gindra, Philipp Putze, 康森柏 Kang Senbai, Giovanni Palla, Tina Šket, Chiara Falcomatà, C Wang, R. Guo, Melanie Boxberg, Luc M. Berclaz, Lars Hartwin Lindner, Linda Bergmayr, Thomas Knösel, Philipp Jurmeister, , Tingying Peng

Phoenix predicts spatially resolved single-cell gene expression from histology, identifying new biomarkers and validating them across cancers and treatment regimens.

bioRxiv · May 7, 2026 · PreprintBioinformatics