Chiara Falcomatà

Phoenix predicts spatially resolved single-cell gene expression from histology, identifying new biomarkers and validating them across cancers and treatment regimens.

This paper generates cross-species single-cell atlases of pancreatic cancer to study progression, therapy response, and immune evasion across human and mouse models.

This study identifies Serpinb2 and Serpine1 as key factors in pancreatic cancer that remodel the tumor microenvironment to promote immune evasion and tumor progression.

This paper develops a method to conjugate bispecific antibodies to lipid nanoparticles for targeted mRNA delivery, showing improved efficiency and specificity in transfecting specific cell types.