DnaJC7 specifically regulates tau seeding
Valerie A. Perez, David W. Sanders, Aydé Mendoza‐Oliva, Barbara Elena Stopschinski, Vishruth Mullapudi, Charles L. White, Łukasz A. Joachimiak, Marc I. Diamond
This study identifies DnaJC7 as a specific regulator of tau seeding through its interaction with Hsp70, showing that its protective activity depends on the J domain and substrate binding site.
eLife · Jun 30, 2023Peer-reviewedMolecular Biology