Author

Hannah J. O’Toole

University of California, DavisORCID 0000-0002-1843-9332Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

Randy P. CarneyiD· 3 shared Elizabeth J. HaleiD· 2 shared Neona M. LoweiD· 2 shared Anchaleena James· 1 shared Anna V. KolesoviD· 1 shared Anthony S. WexleriD· 1 shared Anthony ValenzuelaiD· 1 shared Bhupinder S. ShergilliD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersBioengineering

Randy P. CarneyORCID

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3 papers

Recent·Most cited

BioengineeringAdvanced Healthcare MaterialsPeer-reviewedMar 21, 2026

A physiological microfluidic blood-brain-barrier model for in vitro study of nanoparticle trafficking and accumulation

Bryan B. Nguyen, Neona M. Lowe, Sophia Kellogg…·Randy P. Carney

The paper develops a microfluidic BBB model to study nanoparticle trafficking and accumulation, finding that ligand presentation and membrane composition, not size or stiffness, govern BBB penetration.

3 citationstop 3%

humanexperimental assay

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Pharmacology & ToxicologyEnvironmental PollutionPeer-reviewedJan 27, 2026

Spatial and spectral mapping of traffic-related air pollution (TRAP) nanoparticles in relation to plaques and inflammatory markers in an Alzheimer disease model

Hannah J. O’Toole, Anchaleena James, Nathifa Nasim…·Randy P. Carney

This study maps TRAP-derived nanoparticles in an Alzheimer model, finding sex- and region-specific effects on neuroinflammation and plaque interactions.

DOI 10.1016/j.envpol.2026.127730

ratimaging

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BiophysicsJournal of Extracellular VesiclesPeer-reviewedSep 1, 2024

Plasma-derived extracellular vesicles (EVs) as biomarkers of sepsis in burn patients via label-free Raman spectroscopy

Hannah J. O’Toole, Neona M. Lowe, Vishalakshi Arun…·Randy P. Carney

This study uses Raman spectroscopy to detect sepsis in burn patients by analyzing plasma-derived extracellular vesicles, achieving high sensitivity and specificity.

24 citationstop 4%

humanproteomics

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