Author

Luis Fayad

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-1844-5548Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Christopher R. FlowersiD· 2 shared Hun Ju LeeiD· 2 shared Jason R. WestiniD· 2 shared Loretta J. NastoupiliD· 2 shared Paolo StratiiD· 2 shared Sattva Swarup NeelapuiD· 2 shared Swaminathan P. IyeriD· 2 shared Aneela Syeda AbediniD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersCancer Biology

Christopher R. FlowersORCID

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2 papers

Recent·Most cited

A patient derived xenograft repository capturing clinical and molecular heterogeneity of large B-cell lymphoma

Haopeng Yang, Kotaro Arita, Kevin Bowman, Dai Chihara, Jared M. Henderson, Griffin Rost, Estela Rojas, Sydney Parsons, Priya Lakra, Aneela Syeda Abedin, Sattva Swarup Neelapu, Paolo Strati, Loretta J. Nastoupil, Luis Fayad, Swaminathan P. Iyer, , Michael R. Green

The paper establishes a PDX repository of large B-cell lymphoma models capturing clinical and molecular diversity, including post-CART19 progression cases.

Blood Cancer Discovery · Jun 24, 2026Peer-reviewedCancer Biology

Clonal hematopoiesis is associated with increased toxicity in large B-cell lymphoma patients treated with chimeric antigen receptor T cell therapy

Neeraj Y. Saini, David M. Swoboda, Uri Greenbaum, Jungsheng Ma, Romil D. Patel, Kartik Devashish, Kaberi Das, Mark R. Tanner, Paolo Strati, Ranjit K. Nair, Luis Fayad, Sairah Ahmed, Hun Ju Lee, Swaminathan P. Iyer, Raphael Eric Steiner, , Koichi Takahashi

This study finds that clonal hematopoiesis mutations, particularly in DNMT3A, TET2, and ASXL1, are linked to increased toxicity in patients undergoing anti-CD19 CAR T-cell therapy for large B-cell lymphoma.

bioRxiv · Sep 28, 2021 · PreprintGenetics