NeurosciencebioRxivPreprint
Competition between distinct ApoE alleles and mCRP for the endothelial receptor CD31 differentially regulates neurovascular inflammation and Alzheimer's disease pathology
Zhengrong Zhang, Hana Na, Qini Gan…·Wei Qiao Qiu
The paper shows that ApoE alleles compete with mCRP for CD31 binding on brain endothelia, leading to differential AD pathology based on ApoE genotype.