Author

Qini Gan

Boston University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

Wei Qiao QiuiD· 2 shared Andrew EmiliiD· 1 shared Angelo GaitasiD· 1 shared Balaji KrishnaniD· 1 shared Benjamin L. WoloziniD· 1 shared Bin GongiD· 1 shared Ernesto G. Miranda-MoralesiD· 1 shared Hana Na· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Wei Qiao QiuORCID

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2 papers

Recent·Most cited

Circulating exosomes from Alzheimer's disease suppress VE-cadherin expression and induce barrier dysfunction in recipient brain microvascular endothelial cell

Jiani Bei, Ernesto G. Miranda-Morales, Qini Gan, Yuan Qiu, Sorosh Husseinzadeh, Jia Yi Liew, Qing Chang, Balaji Krishnan, Angelo Gaitas, Subo Yuan, Michelle Madden Felicella, Wei Qiao Qiu, Xiang Fang, Bin Gong

This study shows that Alzheimer's disease circulating exosomes reduce VE-cadherin expression and impair brain endothelial barrier function through RNA cargo-dependent mechanisms.

bioRxiv · Apr 3, 2023 · PreprintNeuroscience

Competition between distinct ApoE alleles and mCRP for the endothelial receptor CD31 differentially regulates neurovascular inflammation and Alzheimer's disease pathology

Zhengrong Zhang, Hana Na, Qini Gan, Qiushan Tao, Yuriy O. Alekseyev, Junming Hu, Zili Yan, Jack B. Yang, Hua Tian, Shenyu Zhu, Qiang Li, Ibraheem M. Rajab, Jan Krzysztof Blusztajn, Benjamin L. Wolozin, Andrew Emili, , Wei Qiao Qiu

The paper shows that ApoE alleles compete with mCRP for CD31 binding on brain endothelia, leading to differential AD pathology based on ApoE genotype.

bioRxiv · May 30, 2021 · PreprintNeuroscience