Hannah E. Augustijn

The paper constructs a regulatory atlas of Streptomyces and related actinomycetes using DAP-seq and ChIP-seq, revealing conserved and divergent transcriptional networks.

plantiSMASH 2.0 improves detection, annotation, and prioritization of plant biosynthetic gene clusters by expanding BGC types and adding substrate prediction and regulatory analysis.

The paper discovers a new class of bile salt hydrolases in the human gut microbiome that use metal cofactors instead of the typical Ntn mechanism.

LogoMotif provides a database of transcription factor binding sites in Actinobacteria, including position weight matrices and predicted interactions, to aid in gene regulation and compound discovery.

FERMO is a dashboard that automates the prioritization of molecular features from mass spectral data to link molecules to phenotypes.

BiG-MAP profiles metabolic gene cluster abundance and expression in microbiomes, identifying clusters associated with oral health and disease.

This study systematically profiles primary metabolic genes in the human gut microbiota, revealing pathway differences among phyla and showing limited correlation between gene abundance and metabolite levels in plasma.