Palmitoylation Couples DLK to JNK3 to Facilitate Pro-degenerative Axon-to-Soma Signaling
Jingwen Niu, Sabrina M. Holland, Andrea Ketschek, Kaitlin M. Collura, Takashi Hayashi, Gianluca Gallo, Gareth M. Thomas
This study identifies mechanisms explaining why DLK couples to JNK3 rather than other MAPKs, showing JNK3 palmitoylation facilitates pro-degenerative axon-to-soma signaling.
bioRxiv · Nov 17, 2020 · PreprintNeuroscience