Author

Daniel M. Richards

University of Massachusetts Chan Medical SchoolORCID 0000-0002-1876-1700Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Qing YuiD· 2 shared Shaoxian LiiD· 2 shared Anthony A. IannettaiD· 1 shared Bohui Li· 1 shared Fangyi Zhai· 1 shared Hua XuiD· 1 shared Ka YangiD· 1 shared Kevin Dong· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBiochemistry

Qing YuORCID

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2 papers

Recent·Most cited

BiochemistryJournal of Proteome ResearchPeer-reviewedSep 9, 2026

Systematic Characterization of Thermal Stability Assay Parameters and Application in Discovery of Peptide-Protein Interactions

Daniel M. Richards, Fangyi Zhai, Shaoxian Li, Qing Yu

This study systematically evaluates PISA assay parameters and applies them to discover a new peptide-protein interaction involving angiotensin II.

1 citation

humanproteomics

Cell BiologyACS Chemical BiologyPeer-reviewedMay 29, 2026

Analysis of Confounding Factors in Reactive Cysteine Profiling Reveals Enhanced Chromatin-Protein Association via CDK7 Inhibition by THZ1

Ka Yang, Shaoxian Li, Bohui Li…·Qing Yu

This study compares cysteine ligandability in live cells and native lysates, identifying factors like accessibility, abundance, and relocalization, and shows THZ1 induces chromatin binding.

DOI 10.1021/acschembio.6c00101

proteomicsexperimental assay