Author

Roxana E. Georgescu

Howard Hughes Medical InstituteORCID 0000-0002-1882-2358Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Assay:DNA methylation· 1 Organism:E. coli· 1

Frequent Co-Authors

Mike E. O’DonnelliD· 2 shared Fengwei ZhengiD· 1 shared Huilin LiiD· 1 shared Meinan LyuiD· 1 shared Nina Y. YaoiD· 1 shared Ryan MayleiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Mike E. O’DonnellORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiochemistryMolecular CellPeer-reviewedMay 14, 2026

The E. coli DnaX clamp loader sharply bends DNA to load β-clamp at nicks and small gaps

Fengwei Zheng, Nina Y. Yao, Roxana E. Georgescu…·Huilin Li

This paper shows the E. coli DnaX clamp loader uses DNA bending instead of unwinding to load β-clamp at nicks and small gaps, revealing a distinct bacterial mechanism for DNA repair.

1 citation

E. coliDNA methylation

𝕏 PostBluesky

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedSep 10, 2025

DNA polymerase α-primase can function as a translesion DNA polymerase

Ryan Mayle, Roxana E. Georgescu, Mike E. O’Donnell

This study shows DNA polymerase α-primase can bypass oxidized or hydrolyzed template nucleotides, explaining why it lacks a proofreading exonuclease.

2 citations

experimental assaychromatin & epigenetic regulation

𝕏 PostBluesky