Systems BiologyPLoS Computational BiologyPeer-reviewed
Spatiotemporal Modeling of GPCR Signaling: The Role of Endosomal Dynamics and Receptor Recycling
Chloé Weckel, J Gourdon, Léo Darrigade…·Romain Yvinec
This study develops a mathematical framework integrating receptor trafficking and signaling compartmentalization to analyze how GPCR internalization and recycling affect ligand-induced responses.
DOI 10.1371/journal.pcbi.1014790