Author

Léo Darrigade

Université de ToursORCID 0000-0002-2367-3414Unclaimed ORCID profile · follow to get notified of new preprints

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Systems Biology· 1

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Approach:statistical model· 1

Frequent Co-Authors

Chloé WeckeliD· 1 shared Éric ReiteriD· 1 shared Frédéric Jean‐AlphonseiD· 1 shared J GourdoniD· 1 shared Pascale CrépieuxiD· 1 shared Romain YvineciD· 1 shared Stefan HaariD· 1 shared Vinesh JugnarainiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperSystems Biology

Chloé WeckelORCID

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1 paper

Recent·Most cited

Systems BiologyPLoS Computational BiologyPeer-reviewedSep 29, 2026

Spatiotemporal Modeling of GPCR Signaling: The Role of Endosomal Dynamics and Receptor Recycling

Chloé Weckel, J Gourdon, Léo Darrigade…·Romain Yvinec

This study develops a mathematical framework integrating receptor trafficking and signaling compartmentalization to analyze how GPCR internalization and recycling affect ligand-induced responses.

DOI 10.1371/journal.pcbi.1014790

statistical model

𝕏 PostBluesky