Author

Joana Saavedra

Universidade do PortoORCID 0000-0002-1920-2361Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

Isabel CardosoiD· 3 shared Tiago GiãoiD· 3 shared Alexandre DiasiD· 1 shared António J. FigueiraiD· 1 shared Cláudio M. GomesiD· 1 shared Gemma ArsequelliD· 1 shared Inês BaldeirasiD· 1 shared Isabel J. SantanaiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Isabel CardosoORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Neuronal expression of S100B triggered by oligomeric Aβ peptide protects against cytoskeletal damage and synaptic loss

Joana Saavedra, Mariana Nascimento, António J. Figueira, Marina I. Oliveira da Silva, Tiago Gião, João Filipe Oliveira, Márcia A. Liz, Cláudio M. Gomes, Isabel Cardoso

This study shows that neuronal S100B expression is triggered by Aβ oligomers and protects against cytoskeletal damage and synaptic loss in Alzheimer's disease.

bioRxiv · Apr 4, 2025 · PreprintNeuroscience

Transthyretin Levels and Instability in Alzheimer's Disease: Correlations with AD Biomarkers in a Cohort Study

Tiago Gião, Miguel Tábuas‐Pereira, Inês Baldeiras, Joana Saavedra, Alexandre Dias, Maria João Saraiva, Maria Rosário Almeida, Isabel J. Santana, Isabel Cardoso

This study examines TTR levels and instability in plasma and CSF across AD stages, finding associations with amyloid-beta, tau, and neuroinflammation markers.

bioRxiv · Jan 24, 2025 · PreprintNeuroscience

Neuroprotection in early stages of Alzheimers Disease is promoted by Transthyretin angiogenic properties

Tiago Gião, Joana Saavedra, José Ricardo Vieira, Marta Teixeira Pinto, Gemma Arsequell, Isabel Cardoso

This study shows that transthyretin (TTR) promotes angiogenesis and vascular health in Alzheimer's disease, with tetrameric stabilization offering a potential therapeutic strategy.

Alzheimer s Research & Therapy · Aug 24, 2021Peer-reviewedMolecular Biology