The Role of Fibrinogen-Mediated Platelet Aggregation in Subsequent Platelet-Driven Blood Clot Contraction
Alina I. Khabirova, Хисматуллин Рафаэль Рафикович, Shakhnoza M Saliakhutdinova, Natalia G. Evtugina, Lorena Buitrago, Prashant K. Purohit, Литвинов Рустем Игоревич, John W. Weisel
This study shows that blocking fibrinogen-mediated platelet aggregation with RGDW peptide delays and slows clot contraction without affecting final clot shrinkage.
bioRxiv · Jun 25, 2026 · PreprintCell Biology