NeurosciencebioRxivPreprint
Disrupted mannosidase enzymes in C9orf72 ALS/FTD
Briana N Ondatje, Lauren M Gittings, Kim R Preller…·Rita Sattler
The paper identifies reduced Golgi enzymes MAN1A1 and MAN1A2 in ALS-associated microglia and astrocytes, linking impaired glycan metabolism to neuroinflammation and disease mechanisms.
DOI 10.64898/2026.10.30.763135