Author

Bessie Meechoovet

Translational Genomics Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Organism:human· 4 Research Focus:differential expression· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Eric B. AlsopiD· 3 shared Kendall R. Van Keuren‐JenseniD· 3 shared Anna BonfittoiD· 2 shared Elizabeth D. HutchinsiD· 2 shared Jerry Antone· 2 shared Matthew J. HuentelmaniD· 2 shared Patrick PirrotteiD· 2 shared Rebecca A. Reiman· 2 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersNeuroscience

Eric B. AlsopORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Disrupted mannosidase enzymes in C9orf72 ALS/FTD

Briana N Ondatje, Lauren M Gittings, Kim R Preller, Eric Alsop, Krystine Garcia-Mansfield, Nate Hansen, Brooke Lovell, Ritin Sharma, Ignazio S Piras, Melissa Martinez, Bessie Meechoovet, Anna Bonfitto, Serena Song, Jennifer Levy, Matt Huentelman, , Rita Sattler

The paper identifies reduced Golgi enzymes MAN1A1 and MAN1A2 in ALS-associated microglia and astrocytes, linking impaired glycan metabolism to neuroinflammation and disease mechanisms.

bioRxiv · Nov 4, 2026 · PreprintNeuroscience

State-dependent release of extracellular particles with distinct α2,6-sialylation patterns and small RNA cargo related to neuroinflammation

Marta García-Contreras, Carinna Lima, Eric B. Alsop, Balazs Kaszala, Bessie Meechoovet, B. A. Purnell, Nan Jiang, András Saftics, Candice Tang, Olivia D Walsh, Sophia Holland, Jimmy Fay, Barbara Lynn Smith, Krishna P. Sigdel, Kendall R. Van Keuren‐Jensen, , Saumya Das

The paper characterizes microglia-derived extracellular vesicles and non-vesicular particles under inflammatory conditions, showing distinct sialylation patterns and small RNA cargo linked to neuroinflammation.

bioRxiv · Oct 30, 2025 · PreprintNeuroscience

The Foundational data initiative for Parkinsons disease (FOUNDIN-PD): enabling efficient translation from genetic maps to mechanism

Elisângela Bressan, Xylena Reed, Vikas Bansal, Elizabeth D. Hutchins, Melanie M. Cobb, Michelle G. Webb, Eric B. Alsop, Francis P. Grenn, Anastasia Illarionova, Natalia Savytska, Ivo Violich, Stefanie Bröer, Noémia Fernandes, Ramiyapriya Sivakumar, Alexandra G. Beilina, , Cornelis Blauwendraat

The paper presents a multi-layered molecular dataset from iPSC-derived dopaminergic neurons to model Parkinson's disease genetic risk and provides a data browser for accessing these resources.

Cell Genomics · Feb 6, 2023Peer-reviewedGenomics

Dynamic Transcriptomic Network Responses to Divergent Acute Exercise Challenges in Young Adults

Kaleen M. Lavin, Zachary Graham, Jeremy S. McAdam, Samia M. O’Bryan, Devin J. Drummer, Margaret B. Bell, Christian J. Kelley, Manoel E. Lixandrão, Brandon Peoples, S. Craig Tuggle, Regina S. Seay, Kendall R. Van Keuren‐Jensen, Matthew J. Huentelman, Patrick Pirrotte, Rebecca A. Reiman, , Marcas M. Bamman

The paper compares transcriptomic responses in skeletal muscle and extracellular vesicles after traditional and high-intensity exercise in young adults, finding more consistent gene responses to traditional exercise and unique microRNA responses to high-intensity training.

bioRxiv · Sep 14, 2022 · PreprintBioinformatics