Author

Lei Huang

Augusta UniversityORCID 0000-0002-1996-944XUnclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Lei Huang2 papers · Human Longevity (United States)

Biology Disciplines

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Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alexandre G.M. MaganiniD· 1 shared Alexandre H. LopesiD· 1 shared André DagostiniD· 1 shared Andrew L. MelloriD· 1 shared Atlante S. MendesiD· 1 shared Conceição Elidianne Aníbal SilvaiD· 1 shared Danielle Santana‐CoelhoiD· 1 shared Denis A. Santana· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Alexandre G.M. MaganinORCID

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2 papers

Recent·Most cited

High resolution analysis of population structure using rare variants

Lei Huang, Thiseas C. Lamnidis, Stephan Schiffels

This paper introduces RAS, a statistical method for analyzing rare variants to detect population structure with higher resolution than common variants, and demonstrates its improved accuracy in ancestry proportion estimation.

bioRxiv · Jul 18, 2025 · PreprintGenetics

Meningeal dendritic cells-astrocytes interactions elevate the kynurenine metabolic pathway to sustain neuropathic pain

Alexandre G.M. Maganin, Guilherme Rabelo de Souza, Miriam M. Fonseca, Alexandre H. Lopes, Rafaela Mano Guimarães, André Dagostin, Nerry T. Cecílio, Atlante S. Mendes, William Antônio Gonçalves, Conceição Elidianne Aníbal Silva, Francisco Isaac Fernandes Gomes, Lucas Maciel Mauriz Marques, Rangel L. Silva, Letícia Arruda, Denis A. Santana, , Thiago M. Cunha

This study identifies the kynurenine metabolic pathway as a key factor in sustaining neuropathic pain through interactions between meningeal dendritic cells and astrocytes.

Journal of Clinical Investigation · Oct 13, 2022Peer-reviewedNeuroscience