Author

Lei Huang

Human Longevity (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Genetics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander E. YarawskyiD· 1 shared Amalio TelentiiD· 1 shared Andrew B. HerriD· 1 shared Bernard ThorensiD· 1 shared C. Thomas Caskey· 1 shared Cameron W. Kenner· 1 shared Catherine T. ChatoniD· 1 shared Christine Leon Swisher· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Alexander E. YarawskyORCID

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2 papers

Recent·Most cited

Enterococcus faecalis autolysin, EpaU, binds the enterococcal polysaccharide antigen via its teichoic acid-like repeats and modulates c-di-AMP signaling

Catherine T. Chaton, Nicholas R. Murner, Svetlana A. Zamakhaeva, Jeffrey S. Rush, Cameron W. Kenner, Alexander E. Yarawsky, Lei Huang, Parastoo Azadi, Andrew B. Herr, Natalia Korotkova, Konstantin V. Korotkov

This study identifies EpaU as an autolysin that binds the enterococcal polysaccharide antigen and modulates c-di-AMP signaling, affecting antibiotic resistance and cell turgor in Enterococcus faecalis.

mBio · Jun 15, 2026Peer-reviewedMicrobiology

Profound perturbation of the human metabolome by obesity

Elizabeth T. Cirulli, Lining Guo, Christine Leon Swisher, Naisha Shah, Lei Huang, Lori A. Napier, Ewen F. Kirkness, Tim D. Spector, C. Thomas Caskey, Bernard Thorens, J. Craig Venter, Amalio Telenti

This study identifies metabolic and genetic signatures of obesity using metabolome analysis and whole genome sequencing in twin and volunteer cohorts, revealing clinically meaningful heterogeneity.

Cell Metabolism · Oct 11, 2018Peer-reviewedGenetics