Thiago M. Cunha

This study identifies GM-CSF as a key mediator of vertebral bone marrow emergency myelopoiesis in neuropathic pain, linking meningeal immunity to pain pathogenesis.

This study identifies TGF-β as a key mediator of macrophage specialization in the skin through interaction with sensory nerves.

This study shows FL/FLT3 signaling increases mechanical pain hypersensitivity via IL-1β in male mice, with IL-1β mediating FL's effects on TRPV1 and pain responses.

This study evaluates the Thermal Gradient Ring as a non-invasive method to assess thermogenesis in mice by analyzing temperature preference and behavior.

This study identifies PD-L1+ neutrophils as mediators of susceptibility to endotoxemia in MAFLD, showing that targeting IFN-γ or PD-L1 reduces inflammation and liver damage.

This study compares how two NET-targeting drugs, rhDNase and GSK484, affect T cell responses in SARS-CoV-2 infection, showing differing impacts on adaptive immunity.

The paper compares CRISPR-Cas9 RNP and nickase systems for inducing Aire gene mutations in murine mTECs, finding recurrent mutations with RNP but not nickase.

This study identifies the kynurenine metabolic pathway as a key factor in sustaining neuropathic pain through interactions between meningeal dendritic cells and astrocytes.

This paper expands the interpretability of human metabolomes by using food-based annotations, increasing the fraction of molecular features understood 7-fold.